Expression of insulin-like growth factor binding protein-1 mRNA in human fetal kidney
نویسندگان
چکیده
منابع مشابه
Optimization and Construction of Human Insulin-like Growth Factor 1 Gene related to human health
Background and aims: Laron syndrome is a disease that treated by Insulin-like Growth Factor 1 (IGF-1). This protein is a single chain and has three disulfide bonds. People with Laron syndrome have low rates of cancer and diabetes, although they appear to be at increased risk of casual death due to their stature. IGF-1 is synthesized by many tissues and is secreted from liver as an endocrine hor...
متن کاملThe role of insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in human esophageal cancer.
BACKGROUND Insulin-like growth factors (1GF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) play important roles in cell growth and differentiation. The aim of this work was to investigate the roles of IGF-1 and IGFBP-3 in esophageal cancer. MATERIALS AND METHODS We examined the circulating IGF-1 and IGFBP-3 concentration in 18 healthy controls and 66 esophageal cancer patients ...
متن کاملMaternal insulin-like growth factor binding protein-1, body mass index, and fetal growth.
AIM To examine the hypothesis that the maternal insulin-like growth factor system may constrain fetal growth. METHODS A prospective observational study of maternal serum insulin-like growth factor binding protein-1 (IGFBP-1) and fetal growth was undertaken in neonates with birthweights below the 5th centile. They had been classified either as having fetal growth restriction (FGR) due to place...
متن کاملVertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3.
BACKGROUND A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined. OBJECTIVE We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with vertex balding in mid...
متن کاملExpression of insulin-like growth factor-binding protein-1 (IGFBP-1) mRNA in embryos and endometrial stromal cells.
The objective of the present study was to investigate the effects of insulin-like growth factor-binding protein-1 (IGFBP-1) on the interaction between mouse embryos and endometrial stromal cells in co-culture systems. To explore quantitatively the changes in expression of IGFBP-1 mRNA from endometrial stromal cells cultured alone or co-cultured with embryos, a combination of reverse transcripti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1992
ISSN: 0085-2538
DOI: 10.1038/ki.1992.343